Hereditary breast and ovarian cancer
Thematic group 3
Hereditary Breast and Ovarian Cancer syndrome (HBOC) is characterized by a high risk of breast and ovarian cancers.
Two genes are associated with the majority of HBOC families: BRCA1 and BRCA2. Other, less common genes associated with an increased risk of developing breast and other cancers, such as PTEN and TP53, are included in Thematic disease group 4 Other rare genturis.
Thematic leads for HBOC in ERN GENTURIS are:
|Judith Balmaña at the Hospital Germans Trias I Pujol in Barcelona, Spain.|
|Darja Molan, board member of Europa Donna Slovenia|
|Salvo Testa, president of MUTAGENS, Italy|