Hereditary breast and ovarian cancer syndrome

Hereditary Breast and Ovarian Cancer Syndrome

Thematic group 3

Hereditary Breast and Ovarian Cancer syndrome (HBOC) is characterized by a high risk of breast and ovarian cancers.

Two genes are associated with the majority of HBOC families: BRCA1 and BRCA2. Other genes less commonly associated with an increased risk of developing breast and other cancers include CHEK2, PTEN and TP53. PTEN and TP53-associated genturis are included in Thematic disease group 4 Other rare genturis. Thematic disease group 4 Other rare genturis.

Thematic leads

Thematic leads for HBOC in ERN GENTURIS are:

Judith Balmaña at the Hospital Germans Trias I Pujol in Barcelona, Spain

Patient representatives

Tamara Hussong Milagre, president of EVITA, Portugal

Darja Molan, president of Europa Donna Slovenia

Salvo Testa, president of MUTAGENS, Italy

A non-exhaustive list of patient associations for genetic tumour risk syndromes in EU member states can be found here.

Healthcare Providers with expertise in Thematic Group 3 Hereditary Breast and Ovarian Cancer (HBOC)

Country	City	Name of Healthcare Provider
Austria	Innsbruck	Medical University of Innsbruck*
Belgium	Brussels	University Hospital Brussels
	Ghent	Ghent University Hospital
	Leuven	University Hospital Leuven
	Liege	University Hospital Liege
Czech Republic	Brno	Masaryk Memorial Cancer Institute
Denmark	Aarhus	Aarhus Universitetshospital
Denmark	Copenhagen	Rigshospitalet
Estonia	Tartu	Tartu University Hospital*
Finland	Helsinki	GENTURISFINSN consortium (HUS Helsinki University Hospital and OYS Oulu University Hospital)
France	Paris	Institut Curie
France	Rouen	Rouen University Hospital
Germany	Dresden	Hereditary Cancer Syndrome Center Dresden
	Erlangen	Universitätsklinikum Erlangen
	Hamburg	Universitätsklinikum Hamburg-Eppendorf
	Hannover	Medizinische Hochschule Hannover
	Munich	Medizinisch Genetisches Zentrum
Hungary	Pécs	University of Pécs
Italy	Bologna	Azienda Ospedaliero-Universitaria di Bologna
	Parma	Azienda Ospedaliero-Universitaria di Parma
	Rome	Fondazione Policlinico Universitario A. Gemelli
	Siena	Azienda Ospedaliero-Universitaria Senese
Latvia	Riga	Pauls Stradins Clinical University Hospital
Lithuania	Vilnius	Vilniaus universiteto ligoninės Santaros klinikos
Netherlands	Amsterdam	Netherlands Cancer Institute - Antoni van Leeuwenhoek
	Groningen	University Medical Center Groningen
	Leiden	Leiden University Medical Center
	Nijmegen	Radboud university medical center
	Rotterdam	Erasmus Medical Center
Norway	Bergen	Haukeland University Hospital*
Poland	Szczecin	Pomeranian Medical University - University Clinical Hospital no 1
Portugal	Lisbon	Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE
Portugal	Porto	Unidade Local de Saúde São João (PT)
Slovenia	Ljubljana	Institute of Oncology Ljubljana
Spain	Barcelona	Hospital Germans Trias I Pujol - lnstitut Catala d'Oncologia
Sweden	Stockholm	Karolinska University Hospital

*These HCPs are Affiliated Partners of ERN GENTURIS

Hereditary Breast and Ovarian Cancer Syndrome

Thematic leads

Patient representatives

Healthcare Providers with expertise in Thematic Group 3 Hereditary Breast and Ovarian Cancer (HBOC)

Country

City

Name of Healthcare Provider